urinary hydroxyproline and osteoporosis

The importance of urinary hydroxyproline and serumal

The importance of urinary hydroxyproline and serumal osteocalcin in the evaluation of post-menopausal osteoporosis Gnudi S(1) Ripamonti C Bonini AM Pratelli L Figus E Author information: (1)Servizio di Medicina Interna Istituto Ortopedico Rizzoli Bologna Forty-nine women aged 49 to 65 who had been in menopause for more than fifteen years were selected on the basis of densitometric

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hydroxyproline assay

hydroxyproline assay manufacturers producers distributors companies organizations service providers list Advanced Search Options : Viewing sites 1 thru 10 of 200: Browse sites by subject Word Count: hydroxyproline assay (200) Next Ningbo Create Biological project Co Ltd Manufacturer: China: Ningbo Create BioChem is a Hi-Tech share-holding company in producing Amino Acids our

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3 Metabolism of Bone and its Remodeling • Functions of

Bone resorption markers include: bone isoenzyme of acid phosphatase (tartrate-resistant) carboxy-terminal telopeptides of collagen (U-ICTP) urinary hydroxyproline or urinary deoxypyridinoline (they are degradation products of collagen cross–links) peptide fragments of collagen with deoxypyridinoline couplings belong to pyridinium compounds)

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Juvenile Paget disease

03/11/2015Juvenile Paget disease is a very rare condition that affects bone growth This condition causes bones to be abnormally large misshapen and easily broken (fractured) Signs and symptoms usually appear in infancy or early childhood As bones grow they become weaker and more deformed This condition affects the entire skeleton resulting in widespread bone and joint pain The bones of the

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Effect of calcium supplementation on urinary

01/06/1984Effect of calcium supplementation on urinary hydroxyproline in osteoporotic postmenopausal women M Horowitz 2 Address reprint requests to: Dr Michael Horowitz Department of Endocrinology Royal Adelaide Hospital North Terrance Adelaide 5000 South Australia Search for other works by this author on: Oxford Academic Google Scholar M Horowitz A G Need Search for other works by this

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Urinary prolyl

Urinary prolyl-hydroxyproline dipeptide as a useful osteomarker easily determined in non-hydrolyzed urine Czech version Authors: P (PHP) as a product of bone turnover to monitor osteoporosis Based on an earlier finding of a high correlation between PHP in non-hydrolyzed urine and hydroxyproline (HP) in hydrolyzed urine we focused on evaluating the correlation between PHP and other

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Evaluation bone resorption activity of childhood nephrotic

Osteoporosis is one of the major side effects in the treatment of nephritic syndrome with glucocorticoids but the exact mechanism of osteopenia is not completely understood Excess glucocorticoids will induce a reduction of bone formation as well as an increase of bone resorption on the other hand Objective To analyze the effect of glucocorticoid on the bone resorption activity of childhood

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New biochemical markers of bone resorption derived from

Abstract The aim of this work was to perform a comparative study between three recently developed biochemical markers of bone resorption derived from collagen metabolism — (1) total urinary free pyridinolines (Pyr) (2) serum pyridinoline cross-linked carboxy-terminal telopeptides of type I collagen (ICTP) and (3) a urinary-specific sequence for a part of the C-telopeptide of the α 1

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Osteoporosis

Osteoporosis Every year osteoporosis causes more deaths than cervical cancer and breast cancer combined Decrease in ability to retain electrolyte balance affects bone metabolism 170 Low potassium intake increases urinary excretion of calcium and phosphorous 171 Although association doesn't necessarily signify causation it is more than coincidence that the rise in osteoporosis and other bone

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The Role of Biochemical Tests in the Screening and

The Role of Biochemical Tests in the Screening and Monitoring of Osteoporosis Show all authors Christopher P Price Christopher P Price See all articles by this author Search Google Scholar for this author Paul W Thompson 1 Paul W Thompson Department of Rheumatology Poole General Hospital Longfleet Road Poole Dorset BH15 2JB UK See all articles by this author Search Google Scholar

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[PDF] Urinary N

The active zone is a unique specialization of the presynaptic membrane and is believed to be the site of transmitter release The formation of the active zone and the relationship of this process to transmitter release were studied at reinnervated neuromuscular junctions in the frog At different times after a nerve crush the cutaneous pectoris muscles were examined with intracellular

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Laboratory Procedure Manual

standard treatment for Paget's disease of bone have been developed to treat osteoporosis The anti-resorptive properties of bisphosphonates decrease bone remodeling and consequently decrease the overall loss of bone Biochemical markers are useful in monitoring metabolic bone disease Urinary hydroxyproline and total

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Ipriflavone in the Treatment of Postmenopausal

Figure 3 shows the changes in serum alkaline (Figure 3A) in urinary hydroxyproline corrected for creatinine (Figure 3B) and in urinary CrossLaps corrected for creatinine (Figure 3C) We found no statistically significant difference between the 2 treatment groups for any of the biochemical markers of either bone formation or bone resportion

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Spinal osteoporosis in men — Indiana University School

Plasma alkaline phosphatase (P 0 02) was increased but urine hydroxyproline and calcium excretion were not significantly raised Calcium balance was negative due to failure of absorption to match urinary calcium loss and radiocalcium absorption (P 0 01) and plasma 1 25-dihydroxyvitamin D (P 0 05) were reduced Original language: English (US) Pages (from-to) 347-357: Number of pages: 11

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RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES

menopausal osteoporosis women With this view we planned to assess the osteoclastic activity by determining Urinary Hydroxyproline in osteoporotic women Hydroxyproline is a derivative of proline a non-essential glucogenic amino acid It is incorporated into the proteins then hydroxylated to hydroxyproline by the enzyme prolyl hydroxylase

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Clinical Briefs: Ipriflavone for Osteoporosis

Clinical Briefs With Comments from John La Puma MD FACP Ipriflavone for Osteoporosis July 2001 Volume 4 84 Source: Alexandersen P et al Ipriflavone in the treatment of postmenopausal osteoporosis: A randomized controlled trial JAMA 2001 285:1482-1488 Data on the efficacy and safety of ipriflavone for prevention of postmenopausal bone loss are conflicting

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Prevent osteoporosis

Urinary hydroxyproline was significantly decreased in ipriflavone treated patients suggesting a reduction in bone turnover rate A reduction of incident vertebral fractures was observed in ipriflavone treated women compared with control subjects The data indicated that long-term treatment with ipriflavone may be considered safe and may increase bone density and possibly prevent fractures

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Biochemical markers of bone metabolism as they relate

Urinary hydroxyproline however is not specific for bone function because it is influenced by various diseases and other factors including diet The use of a spot second-voided urine specimen obtained after an overnight fast may avoid the influence of dietary hydroxyproline [14] Methods for measuring hydroxyproline include photometry fluorometry and high pressure liquid chromatography (HPLC)

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Early Diagnosis of Osteoporosis in Postmenopausal Women

osteoporosis may exceed 30 to 40% In women there is a 15 to 18% risk of hip fracture after the age of 50 years Orthocresolphthalein complexone method5 6 Urinary Hydroxyproline was estimated by Modified Neumann and Logan method7 8 9 STATISTICAL ANALYSISStatistical analysis of biochemical parameters done by unpaired„t‟ test III Observations Table 1: Age Wise Distribution Of

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Calcitonin

Duration calcitonin-salmon: 6-8 hr for hypercalcemia t 1/2: 60 min for calcitonin-human and 43 min for calcitonin-salmon The onset of calcitonin-human in reducing serum alkaline phosphatase level and urinary hydroxyproline excretion in Paget's disease may take 6-24 months Metabolized to inactive compounds in the kidneys blood and peripheral tissues

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Prevention and Treatment of Glucocorticoid

Since the discovery of cortisol and the synthesis of related compounds these potent pharmacologic agents have been progressively more widely utilized in allergic pulmonary and rheumatologic conditions Organ transplantation represents a new group of patients added to the already large pool of subjects receiving glucocorticoids However glucocorticoids cause major side effects involving

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