propane-1 2-diol toxicity

sensiva PA 20

3-(2-ethylhexyloxy)propane -1 2-diol : Genotoxicity in vitro : Not mutagenic in Ames Test OECD 471 Genotoxicity in vivo : Micronucleus test: not mutagenic OECD 474 Carcinogenicity No data available Reproductive toxicity Components: 3-(2-ethylhexyloxy)propane-1 2-diol: Effects on foetal develop-ment

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Zep Gold Touch 4

Reproductive toxicity no data available DIPA Coconate: Fatty acids C8-18 and C18-unsatd compds with diisopropanolamine: Alcohols C10-14 ethoxylated: propane-1 2-diol: sodium xylenesulphonate: STOT - single exposure no data available STOT - repeated exposure no data available Aspiration toxicity no data available Further information Product:

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EHS L TEXT(CED

propane-1 2-diol 57-55-6 200-338-0 - - 1- 5%W/W naphtha-lenesulfonic acid dimethyl- polymer with formaldehyde and methyl-naphtha-lenesulfonic acid sodium salt Xi R36/38 Eye Irrit 2 H319 Skin Irrit 2 H315 1- 5%W/W Substances for which there are Community workplace exposure limits

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# ExpertCare Ear Cleaning Rinse

ExpertCare Ear Cleaning Rinse Version 2 0 Revision Date 04/17/2013 Page 5 of 9 Acute oral toxicity: Propane-1 2-diol LD50 rat: 22 000 mg/kg Benzyl Alcohol LD50 rat: 1 230 mg/kg Acute inhalation toxicity: Propane-1 2-diol LC50 rabbit: 317 mg/l 2 h Benzyl Alcohol LC50 rat: 4 1 mg/l 4 h Acute dermal toxicity: Propane-1 2-diol

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qScript XLT One

qScript XLT One-Step RT-qPCR ToughMix Version 1 1 Revision Date 08/21/2015 Print Date 08/25/2015 6 / 11 Acute oral toxicity : No data available Acute inhalation toxicity : No data available Acute dermal toxicity : No data available Ingredients: propane-1 2-diol : Acute oral toxicity :

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Kleenex Ultra Hand Cleanser (6330)

propane-1 2-diol: Toxicity to fish : LC50 (Fish): 40 613 mg/l Exposure time: 96 h Toxicity to daphnia and other aquatic invertebrates : EC50 : 18 340 mg/l Exposure time: 48 h 12 2 Persistence and degradability Product: Biodegradability : Remarks: No information available

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Safety Data Sheet according to Regulation (EC) No1907/2006

Safety Data Sheet according to Regulation (EC) No1907/2006 Page 1 of 17 LOCTITE ABLESTIK UV 9110-9 known as ECCOBOND UV monoester with propane-1 2-diol Phosphine oxide bis(2 6-dimethoxybenzoyl)(2 4 4- Acute toxicity Category 3 H331 Toxic if inhaled Route of Exposure: Inhalation Acute toxicity Category 4

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Re‐evaluation of propane‐1 2‐diol esters of fatty acids (E

propane-1 2-diol did not raise a concern with respect to genotoxicity the Panel considered that the fatty acid esters of propane-1 2-diol (E 477) did not raise a concern for genotoxicity No chronic toxicity carcinogenicity reproductive and developmental toxicity studies with propane-1 2-diol esters of fatty acids were available to the Panel

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Table 2

The uncertainty regarding the safety of chemicals leaching from food packaging triggers attention In silico models provide solutions for screening of these chemicals since many are toxicologically uncharacterized For hazard assessment information on developmental and reproductive toxicity (DART) is needed The possibility to apply in silico toxicology to identify and quantify DART alerts

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Propane

propane-1 2-diol Not classified Related composition Related composition: Composition 41 Classification open all close all Physical hazards Explosives Acute toxicity - dermal Reason for no classification: data conclusive but not sufficient for classification Acute toxicity - inhalation

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# Solarcaine Aloe Vera Aerosol

Solarcaine Aloe Vera Aerosol Version 2 0 Revision Date 03/17/2016 Page 7 of 11 Propane-1 2-diol Human experience Result: Does not cause skin sensitisation guinea pig Result: Does not cause skin sensitisation Method: OECD 406 Subacute subchronic and prolonged toxicity: Propane-1 2-diol NOEL 50 000 mg/kg Rat Oral Exposure time 24 month

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Aptivus oral solution (finished product)

propane-1 2-diol Propylene glycol 7 % Clean Water Act This product does not contain any Hazardous Substances listed under the U S CleanWater Act Section 311 Table 116 4A This product does not contain any Hazardous Chemicals listed under the U S CleanWater Act Section 311 Table 117 3

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1 IDENTIFICATION OF THE MATERIAL AND SUPPLIER

1 IDENTIFICATION OF THE MATERIAL AND SUPPLIER Synonym(s) CHEEKY WIPES Use(s) BODY WIPES 1 2 Uses and uses advised against 1 3 Details of the supplier of the product Supplier name EDGAR EDMONDSON PTY LTD Address 20 Garden St Marrickville NSW 2204 AUSTRALIA Telephone (02) 9557 4411 Fax (02) 9519 9223 Email ordersedmondson au Emergency

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SAFETY DATA SHEET

Acute toxicity propane-1 2-diol LD50 Dermal Rabbit 20800 mg/kg - LD50 Oral Rat 20 g/kg - (2-methoxymethylethoxy) propanol LD50 Dermal Rabbit 9500 mg/kg - LD50 Oral Rat 5130 mg/kg - Product/ingredient name Result Species Dose Exposure Carcinogenicity Not available Mutagenicity Not available Teratogenicity Not available Reproductive toxicity

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DYNASTY 100FS

propane-1 2-diol 57-55-6 = 1 - 5 Actual concentration or concentration range is withheld as a trade secret SECTION 4 FIRST AID MEASURES SAFETY DATA SHEET Acute toxicity Product: Acute oral toxicity : LD50 (Rat ): 2 000 mg/kg Assessment: The substance or mixture has no acute oral tox-icity

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Re‐evaluation of propane‐1 2‐diol (E 1520) as a food

The toxicity of propane‐1 2‐diol was studies in white growing rats by administration of the substance in the drinking water (Weatherby and Haag 1938) Groups of five male rats at weaning age received concentrations of 0% 0 1% 0 3% 1% 3% or 10% propane‐1 2‐diol in their drinking water for 100 days

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Safety Data Sheet SECTION 1: Identification

Propane-1 2-diol Trade Secret AIHA TWA(asvapouraerosol):10 mg/m3 Propane-1 2-diol Trade Secret Australia OELs TWA(as particulate)(8 hours):10 mg/m3 TWA(as total and particulates)(8 hours):474 mg/m3(150 ppm) ACGIH : American Conference of Governmental Industrial Hygienists AIHA : American Industrial Hygiene Association Australia OELs : Australia

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Safety Data Sheet

ATE = acute toxicity estimate Skin Corrosion/Irritation Name Species Value Propane-1 2-diol propoxylated Rabbit No significant irritation Poly(oxy-1 2-ethanediyl) alpha-hydro-omega-hydroxy-ethane-1 2-diol ethoxylated Rabbit Minimal irritation Serious Eye Damage/Irritation Name Species Value Propane-1 2-diol propoxylated Rabbit No significant

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Safety Data Sheet according to Regulation (EC) No1907/2006

Safety Data Sheet according to Regulation (EC) No1907/2006 Page 1 of 17 SDS No : 450822 V003 0 Revision: 30 06 2014 10- 20 % Specific target organ toxicity - single exposure 3 H335 Skin irritation 2 H315 Serious eye irritation 2 monoester with propane-1 2-diol 27813-02-1 aqua (freshwater) 0 904 mg/L Methacrylic acid monoester with

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